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NDB ID: 7AZO    PDB ID: 7AZO 


Title:

70S THERMUS THERMOPHILUS RIBOSOME WITH BOUND ANTIBIOTIC LEAD SEQ-977

Molecular Description:

Deposited:

2020-11-17

Released:

2022-06-01

Nucleic Acid Sequence:

Click to show/hide 9 nucleic acid sequences

Protein Sequence:

Click to show/hide 48 protein sequences

Primary Citation:

Zhang, J., Lair, C., Roubert, C., Amaning, K., Barrio, M.B., Benedetti, Y., Cui, Z., Li, X., Baurin, N., Bordon-Pallier, F., Cantalloube, C., Sans, S., Blanc, I., Perron, C., Fraisse, L., Rak, A., Jenner, L.B., Yusupova, G., Yusupov, M., Upton, A., Kaneko, T., Yang, T.J., Fotouhi, N., Nuermberger, E., Tyagi, S., Betoudji, F., Sacchettini, J.C., Lagrange, S.
Discovery of natural product derived sequanamycins as potent oral anti-tuberculosis agents
To Be Published, , pp. - , 0.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 209.77   b = 446.87   c = 616.97 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.215 for 860508 reflections in the resolution range 253.87 to 3.3 Ångstroms with Fobs >  1.99 sigma(Fobs) and with I >  0.0 sigma(I)