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NDB ID: 7MW8    PDB ID: 7MW8 


Title:

CRYSTAL STRUCTURE ANALYSIS OF XAC NUCLEOTIDE PYROPHOSPHATASE/PHOSPHODIESTERASE

Molecular Description:

Deposited:

2021-05-15

Released:

2022-05-18

Structural Keywords:

SMALL NA FRAGMENT

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Carozza, J.A., Cordova, A.F., Brown, J.A., AlSaif, Y., Bohnert, V., Cao, X., Mardjuki, R.E., Skariah, G., Fernandez, D., Li, L.
ENPP1's regulation of extracellular cGAMP is a ubiquitous mechanism of attenuating STING signaling. 
Proc.Natl.Acad.Sci.USA, 119, pp. e2119189119 - e2119189119, 2022.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 130.42   b = 66.719   c = 134.961 (Ångstroms)

α = 90.0   β = 116.25   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.2458 for 147590 reflections in the resolution range 30.04 to 1.9 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)