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NDB ID: 7TQB    PDB ID: 7TQB 


Title:

CRYSTAL STRUCTURE OF MONOCLONAL S9.6 FAB BOUND TO DNA-RNA HYBRID

Molecular Description:

Deposited:

2022-01-26

Released:

2022-03-30

Structural Keywords:

A DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 2 protein sequences

Primary Citation:

Bou-Nader, C., Bothra, A., Garboczi, D.N., Leppla, S.H., Zhang, J.
Structural basis of R-loop recognition by the S9.6 monoclonal antibody. 
Nat Commun, 13, pp. 1641 - 1641, 2022.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 1 21 1

Cell Constants:

a = 38.426   b = 158.884   c = 43.142 (Ångstroms)

α = 90.0   β = 105.15   γ = 90.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2317 for 8681 reflections in the resolution range 37.091 to 3.1 Ångstroms with Fobs >  1.38 sigma(Fobs) and with I >  0.0 sigma(I)