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NDB ID: 7TZU    PDB ID: 7TZU 


Title:

CRYSTAL STRUCTURE OF THE E. COLI THIM RIBOSWITCH BOUND TO 1-(4-(PIPERAZIN-1-YL)PYRIDIN-3-YL)-N-(QUINOXALIN-6-YLMETHYL)METHANAMINE (LINKED COMPOUND 38)

Molecular Description:

Deposited:

2022-02-16

Released:

2022-05-25

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Zeller, M.J., Favorov, O., Li, K., Nuthanakanti, A., Hussein, D., Michaud, A., Lafontaine, D.A., Busan, S., Serganov, A., Aube, J., Weeks, K.M.
SHAPE-enabled fragment-based ligand discovery for RNA. 
Proc.Natl.Acad.Sci.USA, 119, pp. e2122660119 - e2122660119, 2022.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 32 1 2

Cell Constants:

a = 61.702   b = 61.702   c = 102.789 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.2336 for 5295 reflections in the resolution range 29.55 to 2.87 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)