A Portal for Three-dimensional Structural Information about Nucleic Acids
As of 3-Aug-2022 number of released structures: 12227
Search for released structures

NDB ID: 7U74    PDB ID: 7U74 


Title:

HUMAN DNA POLYMERASE ETA-DNA TERNARY MISMATCH COMPLEX:REACTION WITH 0.5 MM MN2+ FOR 1800S THEN WITH 10 MM MN2+ FOR 30S

Molecular Description:

Deposited:

2022-03-07

Released:

2022-05-04

Structural Keywords:

B DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 2 nucleic acid sequences

Protein Sequence:

Click to show/hide 1 protein sequences

Primary Citation:

Chang, C., Lee Luo, C., Gao, Y.
In crystallo observation of three metal ion promoted DNA polymerase misincorporation. 
Nat Commun, 13, pp. 2346 - 2346, 2022.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 61

Cell Constants:

a = 98.675   b = 98.675   c = 82.213 (Ångstroms)

α = 90.0   β = 90.0   γ = 120.0 (degrees)

Refinement:

The structure was refined using the PHENIX program. The R value is 0.1924 for 69920 reflections in the resolution range 32.3 to 1.52 Ångstroms with Fobs >  1.36 sigma(Fobs) and with I >  0.0 sigma(I)