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NDB ID: 7WGW    PDB ID: 7WGW 


Title:

NMR SOLUTION STRUCTURE OF A CGMP FILL-IN VACANCY G-QUADRUPLEX FORMED IN THE OXIDIZED BLM GENE PROMOTER

Molecular Description:

Deposited:

2021-12-29

Released:

2022-05-18

Structural Keywords:

QUADRUPLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

No Protein Sequence Found

Primary Citation:

Wang, K.B., Liu, Y., Li, Y., Dickerhoff, J., Li, J., Yang, M.H., Yang, D., Kong, L.Y.
Oxidative Damage Induces a Vacancy G-Quadruplex That Binds Guanine Metabolites: Solution Structure of a cGMP Fill-in Vacancy G-Quadruplex in the Oxidized BLM Gene Promoter. 
J.Am.Chem.Soc., 144, pp. 6361 - 6372, 2022.

Experimental Information:

SOLUTION NMR

Number of Models:

Number of Models: 10 Structures

Sample Details:

1.2 mM None BLM_G18O, 90% H2O/10% D2O 90% H2O/10% D2O