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NDB ID: 7Z4O    PDB ID: 7Z4O 


Title:

INFLUENZA A/H7N9 POLYMERASE CORE DIMER WITH POL II PSER5 CTD PEPTIDE MIMIC BOUND IN SITE 2A

Molecular Description:

Deposited:

2022-03-04

Released:

2022-05-11

Structural Keywords:

RH DOUBLE HELIX

Nucleic Acid Sequence:

Click to show/hide 1 nucleic acid sequences

Protein Sequence:

Click to show/hide 4 protein sequences

Primary Citation:

Krischuns, T., Isel, C., Drncova, P., Lukarska, M., Pflug, A., Paisant, S., Navratil, V., Cusack, S., Naffakh, N.
Type B and type A influenza polymerases have evolved distinct binding interfaces to recruit the RNA polymerase II CTD. 
Plos Pathog., 18, pp. e1010328 - e1010328, 2022.

Experimental Information:

X-RAY DIFFRACTION

Space Group:

P 21 21 21

Cell Constants:

a = 76.474   b = 144.131   c = 336.197 (Ångstroms)

α = 90.0   β = 90.0   γ = 90.0 (degrees)

Refinement:

The structure was refined using the REFMAC program. The R value is 0.0 for 37875 reflections in the resolution range 49.211 to 3.412 Ångstroms with Fobs >  0.0 sigma(Fobs) and with I >  0.0 sigma(I)